Epidermolysis Bullosa

Epidermolysis Bullosa (Butterfly Skin)

Overview

Epidermolysis bullosa (EB) is a group of rare genetic disorders that cause the skin to be extremely fragile and blister easily with minimal friction or trauma. The severity ranges from mild blistering to life-threatening disease depending on the subtype. EB results from mutations in genes responsible for proteins that anchor the layers of skin together.

Key Symptoms

• Skin blisters easily from minor friction, rubbing, or trauma
• Blisters may be widespread or localized depending on subtype
• Erosions, crusting, and slow-healing wounds
• Scarring and milia (small white cysts) at healed blister sites
• Nail dystrophy or nail loss
• Mucous membranes (mouth, esophagus) may also be affected

Affected Areas

Hands, Feet, Knees, Elbows, Trunk, Mucous membranes

Care Instructions

1. Handle skin very gently to minimize friction and trauma.
2. Use non-adherent wound dressings and gentle bandaging techniques.
3. Keep blisters clean and lance large blisters with a sterile needle to prevent extension.
4. Maintain wound care with appropriate topical antibiotics to prevent infection.
5. Work with a specialized EB care team including dermatology, wound care, and nutrition.
6. Genetic counseling is recommended for affected families.

Medical Disclaimer: This information is for educational purposes only and does not replace professional medical advice. Always consult a qualified dermatologist for diagnosis and treatment.

Prevalence: Rare; estimated 1 in 20,000 live births worldwide