Dyshidrotic Eczema

Pompholyx / Dyshidrosis

Overview

Dyshidrotic eczema (pompholyx) is a type of eczema characterized by recurrent crops of intensely itchy, small, clear, fluid-filled vesicles (blisters) on the palms, sides of the fingers, and soles of the feet. Despite its name, it is not related to sweat gland dysfunction. Triggers include stress, contact allergens (especially nickel), atopic dermatitis, and warm/humid weather. Episodes tend to recur and can be debilitating.

Key Symptoms

• Small, intensely itchy, deep-seated vesicles on the palms, sides of fingers, and soles
• Vesicles are firm and may resemble tapioca pearls
• Skin between vesicles may be red and swollen
• Vesicles dry and peel over 2-3 weeks, leaving red, dry, cracked skin
• May merge to form larger bullae in severe cases
• Chronic or recurrent episodes, often worse with stress or warm weather

Affected Areas

Sides of fingers, Palms, Soles of feet, Toes

Care Instructions

1. Apply cold, wet compresses to soothe itching during acute flares.
2. Use potent topical corticosteroids (such as clobetasol) on affected areas as directed.
3. Moisturize hands and feet frequently with thick, fragrance-free emollients.
4. Avoid known triggers: nickel-containing jewelry, harsh soaps, and contact irritants.
5. Wear cotton-lined gloves for wet work and avoid prolonged water exposure.
6. See a dermatologist for persistent or severe cases — phototherapy, oral immunosuppressants, or dupilumab may be considered.

Medical Disclaimer: This information is for educational purposes only and does not replace professional medical advice. Always consult a qualified dermatologist for diagnosis and treatment.

Prevalence: Common; accounts for 5-20% of hand eczema cases