Angioedema

Angioedema

Overview

Angioedema is a sudden swelling of the deeper layers of the skin (dermis and subcutaneous tissue), often occurring around the eyes, lips, tongue, and throat. It can be allergic (histamine-mediated), hereditary (bradykinin-mediated), or medication-induced (commonly from ACE inhibitors). Severe cases involving the airway require emergency treatment.

Key Symptoms

• Sudden swelling of the face, lips, tongue, or throat
• Swelling of hands, feet, or genitals
• Skin may feel tight or tingly before swelling
• Usually not itchy, unlike hives
• Abdominal pain and nausea in hereditary forms
• Difficulty breathing or swallowing if throat is involved (medical emergency)

Affected Areas

Lips, Eyelids, Tongue, Throat, Hands, Feet

Care Instructions

1. Seek emergency medical care immediately if there is throat swelling or difficulty breathing.
2. Antihistamines can help with mild allergic angioedema.
3. Identify and avoid triggers such as medications, foods, or allergens.
4. If caused by an ACE inhibitor, your doctor must discontinue the medication.
5. Carry an epinephrine auto-injector if you have a history of severe episodes.
6. See an allergist for evaluation, especially if episodes are recurrent or the cause is unclear.

Medical Disclaimer: This information is for educational purposes only and does not replace professional medical advice. Always consult a qualified dermatologist for diagnosis and treatment.

Prevalence: Common; affects approximately 15% of the population at some point in their lifetime